Antios Therapeutics Continues Building Experienced Executive Team with Appointments of Katie Laessig, M.D., as SVP, Global Regulatory Affairs and Karen Fusaro as SVP, Clinical Operations

Responsible for managing clinical development and the regulatory processes for ATI-2173, an ASPIN, which is in development as part of a potential curative regimen for chronic hepatitis B infection MENDHAM, N.J., April 27, 2021 (GLOBE NEWSWIRE) – Antios Therapeutics, Inc. (“Antios”) today announced the appointments of two experienced drug development executives, Katie Laessig, M.D., as Senior Vice President, Global Regulatory Affairs, and Karen Fusaro as Senior Vice President, Clinical Operations.

Antios Therapeutics Doses First Patients in SAVE 1, a Phase 2a Study of ATI-2173 in Patients with Chronic Hepatitis B Virus (HBV)

SAVE 1 to evaluate ATI-2173 in combination with tenofovir (TDF) vs. TDF plus placebo SAVE 1 to include cohort of Hepatitis Delta Virus (HDV) co-infected subjects to assess ATI-2173 activity against HDV MENDHAM, N.J., April 21, 2021 (GLOBE NEWSWIRE) – Antios Therapeutics, Inc. (“Antios”) today announced that it has dosed the first patients in its Sustained Anti-Viral Efficacy (SAVE) clinical trial, a Phase 2a study of ATI-2173, an Active Site Polymerase Inhibitor Nucleotide (ASPIN) in clinical development as a backbone of a potentially curative regimen for chronic HBV.

Antios Therapeutics Raises $96 Million in a Series B Financing

Funding will support the Phase 2 clinical program of ATI-2173 in HBV Soleus Capital led the round with new major investors RA Capital Management, Adage Capital Management LP, Pontifax and Aisling Capital as well as Altium Capital, Amzak Health, Granite Point Capital Management, LP, and Life Sci Venture Partners and participating existing investors Lumira Ventures, Cam Capital, Delos Capital, Domain Associates and Sixty Degree Capital MENDHAM, N.J., April 12, 2021 (GLOBE NEWSWIRE) – Antios Therapeutics, Inc.

Antios Therapeutics Appoints Accomplished Financial Executive, Tamra J. Adams, as its first Chief Financial Officer

ATLANTA, Feb. 17, 2021 (GLOBE NEWSWIRE) – Antios Therapeutics, Inc. (“Antios”) today announced the appointment of seasoned financial executive, Tamra J. Adams, as the Company’s chief financial officer (CFO) effective March 1, 2021. Ms. Adams fills a newly created executive position at Antios as part of the Company’s rapid development. “We have recently completed a Phase 1b clinical trial of our lead asset, ATI-2173, a potential backbone treatment in a functional curative regimen for chronic HBV infection, and anticipate presenting proof-of-concept data from the study in mid-2021,” said Gregory Mayes, chief executive officer of Antios.

Antios Therapeutics Appoints Patrick T. Higgins to Board of Directors

Former biopharmaceutical executive has been at the forefront of developing treatments for infectious diseases of the liver including HBV and HCV ATLANTA, Feb. 11, 2021 (GLOBE NEWSWIRE) – Antios Therapeutics, Inc. (“Antios”) today announced the appointment of Patrick T.Higgins to the company’s board of directors. Mr. Higgins is a highly accomplished biopharmaceutical executive with more than two decades of experience leading companies in the development of therapies to treat infectious diseases of the liver including HBV and HCV.

Antios Therapeutics Completes Phase 1b Clinical Trial of ATI-2173, an Active Site Polymerase Inhibitor Nucleotide (ASPIN), in Patients with Chronic Hepatitis B Virus Infection

Study results expected to be presented in mid-2021 ATLANTA, Jan. 25, 2021 (GLOBE NEWSWIRE) – Antios Therapeutics, Inc. (“Antios”) today announced that it has completed the Phase 1b clinical trial of ATI-2173, an Active Site Polymerase Inhibitor Nucleotide (ASPIN), in patients with chronic hepatitis B virus (HBV) infection. The Company expects to present the results of this study at an upcoming major medical conference in mid-2021. “Despite the availability of a vaccine, HBV remains a serious global public health problem with more than 250 million people worldwide living with chronic infection,” said Gregory Mayes, chief executive officer of Antios.

Antios Therapeutics Appoints Gregory T. Mayes Chief Executive Officer

Former CEO and Antios co-founder, Abel De La Rosa, Ph.D., appointed Chairman of the Board of Directors Mayes to lead continued development of ATI-2173 as a potential backbone of a curative regimen for Hepatitis B (“HBV”) ATLANTA, Dec. 01, 2020 (GLOBE NEWSWIRE) – Antios Therapeutics, Inc. (“Antios”) today announced the appointment of Gregory T. Mayes as Chief Executive Officer and Director. Mr. Mayes succeeds Abel De La Rosa, Ph.D., who co-founded Antios in 2018 and has served as CEO and Director since its inception.

Antios Therapeutics Presents at EASL Digital International Liver Congress 2020

ATLANTA, Sept. 3, 2020 /PRNewswire/ – Antios Therapeutics, Inc. (“Antios”), a biopharmaceutical company focused on the development of innovative therapies to treat and cure viral diseases, today announced a digitally available oral presentation at the European Association for the Study of the Liver (EASL) Digital International Liver Congress™ 2020. The title of the abstract (SAT-422) presented is as follows: “ATI-2173, A Novel Phosphoramidate Nucleoside Prodrug for HBV Cure Regimens”

Antios Therapeutics Announces Publication Describing Preclinical Profile of ATI-2173

ATLANTA, Sept. 1, 2020 /PRNewswire/ – Antios Therapeutics, Inc. (“Antios”), a clinical-stage biopharmaceutical company focused on the development of innovative therapies to treat and cure viral diseases, announced today the publication of preclinical results of ATI-2173, Antios’ lead oral drug candidate for treating patients infected with Hepatitis B virus (HBV). The manuscript, published in the peer-reviewed journal Antimicrobial Agents and Chemotherapy and titled ATI-2173, a Novel Liver-Targeted Non-Chain-Terminating Nucleotide for Hepatitis B Virus Cure Regimens, described ATI-2173 as a selective inhibitor of HBV with an anti-HBV 50% effective concentration (EC50) of 1.

Antios Therapeutics Announces Notice of Allowance for a U.S. Patent Application Covering ATI-2173

ATLANTA, Feb. 24, 2020 /PRNewswire/ – Antios Therapeutics, Inc. (“Antios”), a clinical-stage biopharmaceutical company focused on the development of innovative therapies to treat and cure viral diseases, announced today that the United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance for U.S. patent application No. 15⁄536,237, titled, “Phosphoramidates for the Treatment of Hepatitis B Virus,” covering the composition of matter and methods of use for ATI-2173, a novel liver-targeted, orally-administered, small molecule against hepatitis B.

Antios Therapeutics Initiates First-in-Human Phase I Study of ATI-2173

ATLANTA, Feb. 12, 2020 /PRNewswire/ – Antios Therapeutics, Inc. (“Antios”), a clinical-stage biopharmaceutical company focused on the development of innovative therapies to treat and cure viral diseases, today announced it has initiated its first-in-human Phase I clinical trial for ATI-2173, a novel liver-targeted, orally-administered, small molecule against hepatitis B. The Phase Ia study is a randomized, double-blind, placebo-controlled single-ascending dose (“SAD”) study in healthy volunteers to evaluate the compound’s safety, tolerability and pharmacokinetic profile.

Antios Therapeutics to present at HEP DART 2019 Meeting

ATLANTA, Ga., Dec. 9, 2019 /PRNewswire/ – Antios Therapeutics, Inc. (“Antios”), a biopharmaceutical company focused on the development of innovative therapies to treat and cure viral diseases, today announced the acceptance of an oral presentation at the 23rd biennial HEP DART meeting being held December 8-12, 2019 in Kauai, Hawaii. Douglas Mayers, M.D., Chief Medical Officer of Antios, will present: “ATI-2173, A Novel HBV Nucleoside Phosphoramidate for HBV Cure Regimens.

Drug Innovation Ventures at Emory (DRIVE) and Antios Therapeutics announce license for hepatitis B drug

Antios raises $25 million in Series A financing Drug Innovation Ventures at Emory (DRIVE) today announced the licensing of ATI-2173, its leading candidate for the treatment of hepatitis B virus (HBV), to Antios Therapeutics (Antios), a biopharmaceutical company focused on the development of novel antiviral therapies for unmet medical needs. “We are very pleased that a DRIVE technology has a chance to positively affect so many patients in need,” says George Painter, PhD, chief executive officer of DRIVE.

Antios Therapeutics Raises $25 Million in Oversubscribed Series A Financing to Pursue Hepatitis B Cure

ATLANTA, Nov. 27, 2018 /PRNewswire/ – Antios Therapeutics, Inc. (“Antios”) today announced the completion of a US$25 million oversubscribed Series A financing led by Lumira Ventures and Domain Associates, two prominent life science venture capital firms. Other investors participating in the financing include CAM Capital, Delos Capital, Quantum Vista Capital, Fonds de solidarite FTQ and Georgia Research Alliance Venture Fund. The proceeds from this financing will be used to develop ATI-2173, Antios’ lead oral drug candidate for treating patients infected with Hepatitis B virus (HBV) and potentially Hepatitis D virus (HDV).